All I can say is - my 2011 DI Equinox (bought brand new) is about to hit 175,000 miles and it’s never drank anything but the cheapest 87 octane fuel (90% Walmart/Murphy’s), and it’s never ingested an ounce of Techron, Berryman’s, or Seafoam ... and no problems.
And not only that, but it’s still all-original parts from the factory. I’ve only changed the Oil & filter (~40 times), battery (twice), brake pads (once), and a purge valve. Even the air filters are still original!! I know ... I know ...
But - my Nox has been taking 900-mile, one-way drives at least 4 times per year (2 round trips), and the last two years it was 8 times (that’s 4 round trips)!!
My conclusion is - running the engine hot on the highway (for an extended time) must be like running the cleaning cycle on a “self-cleaning” oven. It makes using “top-tier” gas, and all these additives, unnecessary.